Last Updated 16\/08\/24<\/p>\n\n\n\n
SPARVASC (SPARsentan in VASCulitis)<\/strong><\/p>\n\n\n\n Cohort study examining endothelin and angiotensin system blockade in ANCA vasculitis.<\/p>\n\n\n\n Recruiting health board: NHS Lothian.<\/p>\n\n\n\n Contact: Neeraj Dhaun (Bean); bean.dhaun@ed.ac.uk<\/a> <\/p>\n\n\n\n MEMRI-Kidney (Manganese-enhanced MRI in Kidney Disease)<\/strong><\/p>\n\n\n\n Identifying patients with acute kidney injury due to ANCA vasculitis at-risk of chronic kidney and cardiovascular disease.<\/p>\n\n\n\n Recruiting health board: NHS Lothian.<\/p>\n\n\n\n Contact: Neeraj Dhaun (Bean); bean.dhaun@ed.ac.uk<\/a> <\/p>\n\n\n\n OCTANE (Optical Coherence Tomography and NEphropathy)<\/strong><\/p>\n\n\n\n Imaging study using optical coherence tomography (OCT) to assess changes in retinal metrics in patients with ANCA-associated vasculitis compared to healthy controls. Serial scans will explore whether metrics are modifiable over time in response to treatment.<\/p>\n\n\n\n Recruiting health board: NHS Lothian.<\/p>\n\n\n\n Contact: Neeraj Dhaun (Bean); bean.dhaun@ed.ac.uk<\/a> <\/p>\n\n\n\n Exploring the role of fibroblasts in disease relapse in Giant Cell Arteritis.<\/strong><\/p>\n\n\n\n Cohort study using transcriptomic, immunohistochemical and in vitro methods to establish the role of fibroblasts in GCA relapse.<\/p>\n\n\n\n Recruiting health board (s): Grampian<\/p>\n\n\n\n PI: Maira Karabayas<\/p>\n\n\n\n Contact details: maira.karabayas@abdn.ac.uk<\/a><\/p>\n\n\n\n The role of Siglec-9 in ANCA associated vasculitis.<\/strong><\/p>\n\n\n\n Translational study aimed at exploring novel mechanisms involving siglecs in ANCA vasculitis. Recruiting health board: NHS Grampian. Contact: dana.kidder@nhs.scot<\/a><\/p>\n\n\n\n Fast Field Cycling imaging as a novel non-invasive approach to evaluate kidney health and disease: a proof-of-concept study. <\/p>\n\n\n\n Recruiting health board: NHS Grampian.<\/p>\n\n\n\n Contact: dana.kidder@nhs.scot<\/a>.<\/p>\n\n\n\n RACEMATE trial.<\/strong><\/p>\n\n\n\n A Randomised Placebo Controlled Trial \u2013 to Explore the Efficacy and Mechanism of Action of Tezepelumab in Eosinophilic Granulomatosis with Polyangiitis.<\/p>\n\n\n\n Recruiting board: NHS Grampian<\/p>\n\n\n\n Contact: dana.kidder@nhs.scot<\/a> or david.miller@nhs.scot<\/a>.<\/p>\n\n\n\n AVACOSTAR<\/strong><\/p>\n\n\n\n Observational study to evaluate safety outcomes for Avacopan in ANCA associated vasculitis.<\/p>\n\n\n\n Recruiting board: NHS GG&C.<\/p>\n\n\n\n